In the United States, there is a significant population of individuals living with diabetes who may develop neuropathy, a type of nerve damage, over time. Approximately 80% of people with diabetes experience some form of neuropathy, which often causes pain or loss of sensation in the extremities. Many patients on current medications still suffer from significant pain. However, Nucynta ( tapentadol 100mg ) has been proven to effectively reduce diabetic peripheral neuropathic pain compared to a placebo. Additionally, data supports the long-term safety and tolerability of this medication.