In the dynamic world of drug discovery, medicinal chemistry services play a pivotal role in the pursuit of novel therapeutic agents. When it comes to identifying potential drug candidates, researchers often find themselves at a crossroads, debating between two fundamental approaches: target-based and phenotypic screening. Each methodology has its unique advantages and challenges, and in this blog, we will explore these approaches while shedding light on a pioneering synthetic chemistry service, TheraIndx, which offers comprehensive support for both strategies.