OxyContin is available in various strengths, including 10mg, 15mg, 20mg, 30mg, 40mg, 60mg, 80mg, and higher doses. The appropriate dosage of OxyContin depends on factors such as the severity of the pain, the patient's tolerance to opioids, and their overall medical condition.

Typically, for opioid-naive patients (those who haven't been regularly taking opioids), the starting dose of OxyContin is often lower than 40mg and is gradually increased under close medical supervision to find the most effective and safe dose for pain relief.