While Malegra can be highly effective in treating erectile dysfunction, smoking can significantly reduce its effectiveness by compromising blood flow and damaging blood vessels. To achieve the best results with Malegra, it is highly recommended to quit smoking or at least reduce tobacco use. Stopping smoking not only improves sexual health but also has broader benefits for overall cardiovascular health and well-being. If you are a smoker and taking Malegra, consult your healthcare provider for advice on how to improve both your sexual and overall health.