You ought to be extremely mindful, particularly when you initially begin taking the medication and however long drowsiness proceeds. On the off chance that sluggishness doesn't disappear, call your primary care physician. They can talk about whether it's safe for you to continue to take this medication. Assuming that you have extreme lethargy, alongside inconvenience breathing or low pulse, call 911 and move clinical assistance immediately. Unreasonable drowsiness with these different side effects might be an indication of excess. Moving clinical consideration immediately is basic for your security. Irritation Oxycodone might make your skin feel bothersome. This is a typical result of the medication. Be that as it may, on the off chance that you're having extreme tingling, with skin rash and flushing, you might be having a serious unfavorably susceptible response to oxycodone. (With flushing, you have transitory warmth, redness, or developing of skin tone.) See the part beneath called "Unfavorably susceptible response" for more data. What could assist Assuming that you have irritation with oxycodone IR oral tablets, talk with your PCP.